Walt Boyes' Blog

Batch "fingerprinting" Having a good batch structure in place is essential for PAT It helps to identify opportunities by allowing online feedback of "atypical process performance" A 1% increase in yield, identified, is worth $2.7 million per year. In the absence of a batch structure process does not know where it is-- It is difficult to determine what the "golden batch" is If … [Read more...] about Joydeep continues his talk…

Joydeep Ganguly and Real-time Bioprocess Monitoring and Control "It isn't enough to have a more sophisticated way of telling you that you have a product that is crappy...that's not PAT. PAT is about consistently creating product that is NOT crappy." CBER monitors the biologicals industry. Talecris is a newly-formed company that inherited the assets of Bayer's plasma … [Read more...] about More from ISA's PAT Conference…

Thank God, ISA has wireless Internet in this conference room! My thumbs were beginning to die from doing the "Blackberry Prayer" too long.Sherman on NeSSI, continuing: Bob showed picures of actual products illustrating the principles of the S76 sample conditioning system...a modular system designed to maximuze efficiency and minimize costs, developed specifically for the … [Read more...] about More from ISA's PAT Conference…

Now, Bob Sherman, author of several books on analyzers and sampling systems, is taking us through the state of ANSI-ISA76- the New Sampling Systems Initiative, or NeSSI. ISA/ANSI-76 is titled, "Sample Conditioning Systems for Process Control Analyzers & PAT/Continuous Improvement Processes." He's provided comparisons (in pictures) of legacy sampling systems and what an … [Read more...] about NeSSI for PAT

Alex Habib has been working on process improvement "since God was a small boy," as they say down here in the South.He showed how the PAT tools can be used in a fermenter using on-line analyzers & SPC software. Then he pointed out that ISA is extremely involved in PAT: Books, training, standards, certification and, of course, trade shows.... Walt Boyes BlackBerry service … [Read more...] about Habib on PAT